A New Method for Measuring
Correlates of Protection
Investigators have proven the effectiveness of using fluorescent targets in phagocytic assays instead of
live infectious agents. FlowApps enhances those methods with a multiplexed cytometric approach by:
- Detecting functional antibodies with differentially labeled fluorescent targets
- Detecting antibody panels for multiple serotypes in a single assay
- Increasing throughput using automation
Speed and Other Benefits
Flow Applications’ approach yields reproducible results similar to those obtained by first generation killing assays by Steiner and Nahm, but at a much higher throughput. With autoloaders, batch analysis, and curve-fitting software, multiplexing technologies deliver even faster results – while enabling vaccine researchers and developers to:
- Accelerate phagocytic assays up to 20 times while reducing serum
and reagent use by up to 75%
- Eliminate biohazards and technical difficulties associated with live bacteria
- Reduce inter- and intra-laboratory variability with established
performance parameters
A Solution for Finding Answers
Flow Applications’ solution is a process platform that includes technology, scientific knowledge, patented methods, and frameworks for best practices. Flow Applications tailors its solutions to its customers’ requirements by:
- Supporting customers with training, collateral materials, and knowledge transfer
- Providing reference laboratory services
- Providing customized assay development services
- Providing standardized reference and control reagents
Flow Applications enables pharmaceutical, biodefense, public health, clinical, and academic research organizations to reduce the time it takes to evaluate immune response pre or post-vaccination. Flow Applications offers its customers a range of options and methodologies that promote efficiencies and cost-effectiveness. |